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Some people also find their sleep gets disturbed after increasing the dose, as the body goes through another adjustment phase

Identification of the peptide and receptors, however, does not by itself substantiate a functional relevance, but evidence for a physiological role of these receptor populations emerged 13 years later and will be discussed here

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Long-Term Strategy and Availability Sometimes, the decision to switch is part of a longer-term treatment strategy developed with a healthcare provider, or it may even be influenced by medication availability, although this should never be the primary driver without proper medical consultation