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1.5 mg once daily for the first month Increased to 4 mg once daily for the second month Then 9 mg once daily for the third month Up to the 25 mg once daily maintenance dose, reached gradually if tolerated It is incredibly important that dose increases are never rushed

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The study did not qualify for prospective registration as a clinical trial because there was no study directed intervention

Syringe Units = Desired Dose (mg)Concentration (mg/mL) 100 Example: a 0.5 mg dose at 5 mg/mL = (0.5 5) 100 = 10 units