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Blood 11(513a), 2000
Glutathione plays a vital role in multiple bodily processes, including detoxification, immune system regulation, and the prevention of cellular damage caused by oxidative stress
b , Total energy expenditure over 24 hours versus body weight after 10 weeks of HFD feeding (Control n = 12, Bmal1-KO n = 12, Bmal1-KO + NDI1 n = 7)
Taken together, these data demonstrate that mitochondrial function is intrinsically linked to 5FU sensitivity, and that its inhibition may provide an opportunity to increase 5FU efficacy
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