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It resets gene expression to a "younger/healthier" state suppressing inflammatory and metastatic genes while activating repair and remodeling genes
This tolerance development explains why side effects are most prominent during treatment initiation and dose escalation but decline substantially with continued use
Patients with tendon and ligament injuries report meaningful improvement in function
This is clearest in complex injuries such as joint damage (cartilage, ligaments, tendons, and bone), surgical wounds (skin, muscle, fascia, and internal tissue), or systemic conditions affecting multiple organs
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