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Brettschneider J, Del Tredici K, Toledo JB, Robinson JL, Irwin DJ, Grossman M, et al
This fermentation leads to the production of SCFAs like butyrate, which are key signals for GLP-1 production in L-cells
A 2024 double-blind randomized trial of 156 participants with early Parkinsons disease found that participants receiving a GLP-1 drug, lixisenatide, showed no progression of motor symptoms, compared to a measurable worsening on standard motor scales in the placebo group
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