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Compensation for X-linked Pdha1 silencing by Pdha2 is essential for meiotic double-strand break repair in spermatogenesis
If a sufficient reduction in HbA 1c levels is not achieved with metformin, treatment is typically escalated by reinforcing the importance of diet and exercise to induce weight loss, and adding a second non-insulin pharmacological treatment (Step 2a)
Nature 588 , 327330 (2020)
True copper allergy typically produces hives, swelling, or systemic symptoms beyond localized skin changes
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