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More serious risks include pancreatitis (requiring immediate medical attention if severe abdominal pain occurs), gallbladder disease, and a boxed warning for medullary thyroid carcinoma risk (contraindicated in patients with personal/family history of MTC or Multiple Endocrine Neoplasia syndrome type 2)

Benzodiazepines can also be overused to the point of becoming ineffective, or you can develop both psychologic and physiologic dependence that makes it hard to stop using the drugs.

422,423,424 Multimodal therapy The curative treatment of EC requires a multimodal approach, reflecting the complex biological characteristics and therapeutic challenges of this disease

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