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However, people taking antidepressants such as selective serotonin reuptake inhibitors (SSRIs) like fluoxetine, serotonin-norepinephrine reuptake inhibitors (SNRIs) like duloxetine, tricyclic antidepressants like amitriptyline, or monoamine oxidase inhibitors such as phenelzine should be aware of the symptoms of serotonin syndrome

These processes involve the activation of muscarinic cholinergic receptors in the forebrain, and an increased expression of type-2 metabotropic glutamate (mGlu2) receptors in dorsal root ganglia neurons

Never leave tirzepatide in a hot car, direct sunlight, or uninsulated bag, as heat accelerates peptide breakdown and reduces efficacy

Testosterone replacement in hypogonadal men has been associated with favourable metabolic effects, including improved lipid profiles and glycaemic control (72)