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It reduces how much energy comes in by suppressing appetite, slowing digestion, and improving how the body handles the food that does get consumed

While it included activation of nuclear hormone receptors that had previously been used in effective drugs with use-limiting side effects, "if you can target those receptors to specific cell types, you might bypass some of the side effects," Habegger said

Bristol Myers Squibb used volume-capped settlement agreements to control the pace of generic entry, which allowed analysts to model the revenue trajectory with unusual precision

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