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Thus, modulating the Fc:FcRn interaction to prolong plasma half-life and attain a favorable biodistribution is a clinical success, and several clinical-stage candidate therapeutics harbor either the YTE or LS amino acid substitutions, or a more recently reported triple Fc mutant variant (Q311R/M428E/N434W
While early-stage EC can be effectively treated through surgical intervention or a combination of radiotherapy, a subset of patients seeks non-surgical treatment options, particularly those desiring to preserve fertility
In a typical, healthy pregnancy, the body has built-in mechanisms to manage this
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