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Phase 3 results, which use larger patient populations and longer follow-up periods, came in somewhat lower
As a consequence, such inactive redox proteins are kinetically uncoupled from the GSH pool
Similarly, alcohol metabolism by CYP2E1 enzyme generates reactive oxygen species including hydrogen peroxide (H2O2), superoxide and hydroxyl radicals which have important roles in causing damage to DNA and in fatty acid oxidation
50% of people in the treatment group lost at least 15% of their body weight over 68 weeks and 86% lost at least 5%
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