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Nat Rev Drug Discovery (2003) 2(9):72735

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Normally, doctors start you on a low dose and gradually increase it to curb gastrointestinal side effects

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Therefore, further investigation of the role of neutrophils in disease development, where phagocytosis is affected by soluble uric acid, may be worthwhile in order to clarify whether sUA is indeed a beneficial immunosuppressive agent

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It is because those areas are commonly used for subcutaneous injections and are easier to inspect, rotate, and avoid when irritated

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