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GLP-1 RAs enhance the regulatory mechanisms of the hypothalamic-pituitary-ovarian axis, affecting LH surges or reductions induced by estrogen aromatization in adipose tissue, and subsequently modulating LH and FSH levels that drive ovarian androgen synthesis [41]
Given tirzepatide shorter half-life of about 5 days, the washout window can be shorter than when switching in the other direction
But did you know that your body naturally produces GLP-1
It contains Glutathione and Arbutin that actively controls the production of melanin pigment
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