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The reaction was terminated by the addition of 400 L phase A (0.1% trifluoracetic acid) before being fractionated into 1 mL volume by reverse-phase high-performance liquid chromatography (RP-HPLC, Waters 600 SimiPrep system) on a C18 column

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Additionally, glutathione neutralizes oxidative stress from environmental factors like UV rays and pollution, which can accelerate aging and dullness

37% of amycretin participants discontinued, though most discontinuations were for non-safety reasons (withdrawal of consent, protocol violations)