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Signaling and Synthesis: The prolonged, unbound presence of IGF-1 LR3 in the bloodstream maximizes the anabolic signaling effect on muscle tissue, activating intracellular signaling pathways that promote protein synthesis and muscle fiber hypertrophy (increase in cell size)

Supplements like Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR) are precursors that the body can use to synthesize NAD+, offering potential avenues for repletion

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