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Introduction Diabetes is a metabolic disease caused by the increased demand for insulin, and is characterized by the relative lack of insulin secretion, the absolute lack of insulin secretion, or insulin resistance, which causes the disorder of sugar, fat, and protein metabolism and makes the patients blood sugar level higher than the standard value(Sami et al

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For example, one meta-analysis demonstrated an average weight loss of 24.15 kg (53 lbs) at 52 weeks with certain GLP-1 receptor agonists (GLP-1RAs)

Increased breakdown of DNA and subsequent accumulation of pyrimidines inhibited the activity of 5-NT