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Therefore, further research is needed to determine whether prolonged GIP receptor antagonism can lead to any adverse effects
Metformin, lifestyle modification, and symptom-specific treatments (combined oral contraceptives, anti-androgens) remain first-line PCOS management per NICE guidance
Search strategy We used the following search strategy: (irritable bowel syndrome OR IBS OR spastic colon OR irritable colon) AND (Glucagon like peptide 1 receptor agonist OR GLP-1 agonist OR Semaglutide OR Dulaglutide OR Exenatide OR Liraglutide OR Lixisenatide OR Tirzepatide)
Medications designed to help patients lose weight can be a source of discouragement if the outcomes arent as hoped
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