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The study demonstrated that NAC effectively reversed PAO-induced corneal injuries, characterized by a concentration- and time-dependent reduction in epithelial layer thickness, which was mediated by ferroptosis induction (115)

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492 Mutant IDH abnormally accumulates D-2-hydroxyglutarate (D-2-HG), triggering epigenetic reprogramming and blockade of cell differentiation, which are particularly prominent in gliomas and hematological malignancies

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By inhibiting COX-2 specifically, it stops prostaglandin production at the source

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