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We next investigated whether mitochondria are the source of ROS generation in RPE cells upon GSH depletion, we used MitoSOX Red to detect mitochondrial ROS (Fig

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It is supplied as a lyophilized powder and reconstituted with bacteriostatic water, added slowly and swirled gently

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First-pass metabolism occurs when a large portion of L-arginine gets broken down by the enzyme arginase in your liver and intestines before it can reach your bloodstream

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