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FDA-approved medications for Cushing's syndrome include osilodrostat (Isturisa), levoketoconazole (Recorlev), pasireotide (Signifor), and mifepristone (Korlym)the latter specifically indicated for hyperglycemia secondary to Cushing's syndrome
In cases of CIRI, an overload of intracellular calcium can trigger stress within the endoplasmic reticulum (Hetz et al., 2020
Compounded preparations are not FDA-approved and not interchangeable with brand-name tirzepatide
Using these alone (without diet and exercise) is unlikely to make any difference
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