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A metabolomic analysis targeting tryptophan metabolism showed that inulin intervention upregulated fecal levels of indole-3-acetate and kynurenine in rats with NAFLD, while downregulating levels of kynurenine and 5-hydroxyindoleacetic acid ( Role of inulin in disease Inulin can regulate the metabolism of glucose, lipids, and amino acids in addition to intestinal immune and systemic immunomodulatory effects
Early receptor and endocrine findings, limited human pharmacology studies, and one proof-of-concept clinical program do not establish an approved indication, general safety, or effectiveness
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[PMID: 1473997] PubMed record related to this compound for laboratory literature review
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