Buse JB, Bajaj HS, Dalskov SM, Donaldson L, Hansen Duus HH, Fabricius TW, Haluzk M, Lingvay I, Pedersen SD, Pratley RE, Jain AB, REIMAGINE 2 study group
Naltrexone, approved in 1984, introduced a non-opioid antagonist that blocked the effects of opioids but required full detoxification before initiation, limiting its early use
Why it matters for body composition: Tesofensine not only reduces caloric intake by controlling hunger but also ramps up basal metabolic rate , making it easier to burn fat while preserving lean muscle, especially when combined with a structured strength training plan
For muscle injuries, strains, or exercise-induced damage, BPC-157 may accelerate repair