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Based on these studies and the functional form of native GLP-1 (736), chimeric proteins as potent GLP-1 agonists with an extended plasma half-life were engineered using a native or two modified human GLP-1 (mGLP-1) that were resistant to DPP-IV or both DPP-IV and trypsin cleavage and fused to a DARPin with high affinity and specificity for HSA
Cercate di dormire almeno 8 ore di sonno ininterrotto per notte
Ca2+-dependent endoplasmic reticulum stress correlates with astrogliosis in oligomeric amyloid -treated astrocytes and in a model of alzheimers disease
Within the oocyte, LC plays a significant role in ER, mitochondria as well as in the ooplasm
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