The compound progressed through Phase 2 trials under multiple sponsors for postoperative ileus and related gastric-motility indications, with one randomized controlled trial published in 2014, but did not advance to a marketed therapeutic in any major jurisdiction
Additionally, hexarelin protects cardiomyocytes from angiotensin II-induced apoptosis by reducing caspase-3 activity, increasing Bcl-2 expression, and inhibiting Bax expression (8)
Together, these peptides support neuroprotection, emotional stability, and cognitive enhancement, offering benefits such as better sleep quality, natural antidepressant effects, and a strengthened immune system
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