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Methods An observational real-world data study assessed patient characteristics and drug utilization in separate SGLT2i and GLP-1 RA new-user cohorts of adults with CKD and type 2 diabetes in an earlier (1 January 201230 June 2021) and a later (9 July 202130 September 2023) period using Optums de-identified Clinformatics Data Mart Database (Optum CDM)

Some individuals experience mild nausea, which paradoxically may contribute to reduced appetite

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This avoids any osmotic disruption from bacteriostatic water