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Pickart & Margolina (Biomedicines, 2018) published a comprehensive review of GHK-Cu's effects on skin biology, documenting its influence on collagen synthesis, glycosaminoglycan production, and fibroblast proliferation in cell culture models
Inhibition of GPX4 activity can result in the accumulation of lipid peroxides, which is a characteristic feature of ferroptosis
7,8 In our previous studies, we found that Clopidogrel inhibits human gastric mucosal epithelial cell line GES-1 proliferation then further disrupt the tight junction structure (TJs) of gastric epithelium, 9 through activation of endoplasmic reticulum (ER) stress-induced apoptosis via MKP-5 -mediated p38/MAPK phosphorylation
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