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Merck discontinued -amino acid-containing molecules due to a lack of selectivity and focused instead on selective amino acid piperazine derivatives, which led to the development of sitagliptin, a compound containing piperazine and triazolopiperazine
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259 Moreover, mitochondrial lipid metabolic remodeling is crucial for cancer cell survival, maintaining energy balance by regulating fatty acid oxidation and mitochondrial function
doi: 10.1080/21505594.2016.1257457 17 CharletR.Le DanvicC.SendidB.Nagnan-Le MeillourP.JawharaS
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