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Although this class was initially proposed as B-cell targeting therapy without cell-line depletion, as BTK plays a role in B-cell receptor activation, this type of molecule has a role in development of myeloid cell line and may also modulate microglial NFkB pathway (180)
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The addition of GSH to the maturation medium resulted in a significant improvement in oocyte quality, as evidenced by the higher proportion of oocytes reaching the MII stage compared to the controls
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