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[Note: Polymorphisms in the genes for CYP enzymes can lead to differences in drug metabolism.] Phagocytosis is the ingestion by receptor-mediated endocytosis of microorganisms, foreign particles, and cellular debris by cells such as neutrophils and macrophages (monocytes)
Activation of melanocortin signaling dopaminergic transmission in mesolimbic pathways
Josefowicz SZ , Lu LF , Rudensky AY
Intravenous administration results in even more rapid excretion with little opportunity for liver storage
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