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This is most relevant in patients with pernicious anaemia receiving initial replacement therapy and requires monitoring of electrolytes

FDA prescribing information for some GLP-1 receptor agonists advises considering discontinuation for sustained increases in resting heart rate

In addition, pharmacological interventions of FAO had obvious effects on IR injury, i.e., the activation of CPT1-dependent FAO by leptin significantly attenuated IR-induced injury, which is manifested by reduced hepatic enzyme level, hepatic injury score, hepatocyte apoptosis, and mitochondrial damage, while the inhibition of CPT1 by etomoxir imparted negative effects

hdl:11384/14713