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Systemic : Inflammation regulation, damage repair, and inter-system communication (e.g., brain, gut, muscles, metabolism)
Frozen storage ( 20 C, and preferably lower for long-term): Recommended for extended timelines, with vials kept well sealed to limit moisture uptake and oxidative degradation
Careful experiments provide an answer
However, your liver can store vitamin B 12 for up to five years, so it's rare for diet to cause this anemia
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