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This makes biological sense - surgery and medication target overlapping but distinct pathways in the bodys weight-regulation system
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However, their signaling diverges at later stages: in the tongue, activation of these receptors produces neurotransmission and conscious taste perception, whereas in the intestine, the same receptor types modulate hormone secretion (such as GLP-1 and GIP) through endocrine signaling pathways (48, 49)
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