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Women who should avoid PT-141 or only use it under close medical supervision include those with: Uncontrolled hypertension Significant cardiovascular disease Known hypersensitivity to melanocortin peptides A history of severe adverse reactions to injectable therapies Pregnancy or breastfeeding PT-141 can cause temporary increases in blood pressure shortly after administration, which is why cardiovascular screening is an important part of the evaluation process

This dose of carnitine was chosen to maximize plasma carnitine concentrations without exceeding the renal threshold for carnitine (8, 23)

This raises common questions: Can PT-141 be taken orally