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High-fat diet decreases cancellous bone mass but has no effect on cortical bone mass in the tibia in mice
Choi IS, An C, Swisher SG , Correa AM, Ajani JA, Rashid A, Hamilton SR, Wu TT
While the pro-inflammatory effect of microcrystalline UA is well-established 3,20 , there are several indications that soluble UA free of UA crystals has protective effects against inflammatory mechanisms and toxicity 50 with effects on macrophage polarisation towards the anti-inflammatory M2 phenotype 51
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