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Conclusion: MTHFR gene mutation testing can provide valuable insights, but its clinical utility and necessity remain debated
With technological advancements, it is possible to design nanoparticles to be able to traverse the blood-brain barrier, increase cellular absorption, and give protection against enzymatic degradation, all of which make them an attractive candidate for delivering siRNA to the brain
GHK-Cu is a tripeptide-copper complex consisting of glycyl-L-histidyl-L-lysine (Gly-His-Lys) bound to a copper(II) ion
The co-cultures are useful as the presence of either astrocytes or pericytes or both cells together with brain endothelial cells improves the BBB characteristics [36, 38, 39, 113, 114]
