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This study provides evidence that modulation of oxidative stress alone is insufficient to rescue behavioral phenotypes in the VPA model of ASD
When oxidative stress is high, speech development frequently slows or becomes uneven
To calibrate the probe, fully oxidized and fully reduced samples were generated by the addition of 20 mM N , N , N , N -Tetramethylazodicarboxamide (diamide, Sigma Aldrich ) or 100 mM Dithiotreitol (DTT, AppliChem ), respectively
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