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It also serves as a required substrate for two important families of enzymes: the sirtuins, which help regulate healthy cellular aging, and the PARPs, which help repair damaged DNA

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Until now, the cause of PD is unknown, but several factors seem to play a role, including environmental factors, such as the pesticide rotenone, that can block mitochondrial functions

If a lump remains hard, grows, or becomes increasingly painful, seek medical evaluation to rule out infection or other complications