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semaglutide: euglycemic diabetic ketoacidosis (n = 32), ketoacidosis (n = 28), and ketosis (n = 8), starvation ketoacidosis (n = 4)
The benefits claimedreversal of aging, improved cognition, enhanced metabolismremain unproven in controlled human trials
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But they hurt more or cause more irritation
Understanding how this dual engagement works at the receptor and cellular level is increasingly relevant for both clinicians and drug discovery teams designing the next generation of incretin mimetics
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