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Most features of CKD-MBD are usually present by the time eGFR falls below 45 (stage 3b), though bone disease can begin as soon as stage 2 (eGFR 60 to 89)
This thorough assessment informs whether microdosing represents an appropriate strategy and what the microdosing GLP-1 dosage should be
For example, GLP-1 analogs have been shown to diminish the desire for sweet, salty, fatty, and savory foods, further supporting their role in shifting food preferences toward less palatable options (Kadouh et al., 2020)
A lack of vitamin B12 can lead to neurological disorders such as agitation, hallucinations, changes in natural reflexes, poor muscle function, memory problems, loss of taste, and in severe cases, can cause psychiatric disorders
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