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AOD-9604 Research Protocols & Administration Dosing in Published Research Research investigations have employed diverse AOD-9604 doses across species and administration routes: Rodent studies: 250-500 mcg/kg orally or intraperitoneally was most common for obesity research Rabbit models: 0.25 mg per joint for osteoarthritis studies (intra-articular injection) Pig pharmacokinetic studies: 1.5 mg/kg IV and 2 mg/kg oral for metabolism characterization Human clinical trials: Oral doses of 0.25-10 mg daily

Last reviewed: May 29, 2026

The cobalamin enters the bloodstream directly and is available to tissues within hours

Vitamin B2, otherwise known as Riboflavin, contributes to normal: energy-yielding metabolism, nervous system function, normal skin and mucous membrane maintenance, red blood cell maintenance, skin health, vision, metabolism of iron, protection of cells from oxidative stress, and reduction of tiredness and fatigue