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Studies thus far suggest semaglutide is generally safe for long-term use, though its been linked to a higher risk of gallbladder issues with longer use
It has been shown to lengthen telomeres in human cells, which is related to longevity
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Curr Neuropharmacol 4:233237 Januszewicz E, Pajak B, Gajkowska B, Samluk L, Djavadian R, Hinton B, Nalecz K (2009) Organic cation/carnitine transporter OCTN3 is present in astrocytes and is up-regulated by peroxisome proliferators-activator receptor agonist
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