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It mimics a naturally occurring hormone that slows digestion, reduces appetite, and helps control glucose levels
Upon the activation of RAGE, excessive ROS formation and increased mitogen-activated protein kinase (MAPK) signaling takes place, further enhancing fibrosis, macrophage adhesion and inflammation and ultimately leading to atherosclerosis and cardiac remodeling (52, 53)
Hypersensitivity Reactions Advise patients that hypersensitivity reactions have occurred with TRESIBA
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