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Its not an apples-to-apples comparison (different study durations and populations), but the numbers suggest retatrutide could potentially surpass Mounjaro when it comes to sheer weight loss efficacy
Lancet 394(10192):3950
The FDA-approved GLP-1 medications come in injectable pens with precise dosing, whereas compounded GLP-1 drugs typically come in a vial with a syringe that can offer more flexibility for microdosing, but also opens up the chance for taking too much or too little medication
Fortunately, evidence-based dietary modifications, medication options, and dosing strategies can effectively manage this side effect
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