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However, an uncontrolled increase in their concentrations leads to a chain of unwanted radical reactions that target the main biomolecules (DNA, RNA, lipids, and proteins) and alters key processes such as nucleic acid oxidation, lipid peroxidation, thereby contributing to the loss of cellular architecture, to impaired cell signalling and, ultimately, to cell death [25, 46]

Yes, it is safe for doctors to prescribe semaglutide for weight loss in non-diabetics

Kolovrat et al., 2020) and venous thrombosis (Vukojevic et al., 2018

In clinical trials, most participants who experienced even moderate GI symptoms were able to continue with appropriate management