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Research Dosing Protocols Based on clinical trial data, most researchers follow a gradual titration protocol: TYPICAL ESCALATION SCHEDULE: Weeks 1-4: 2mg weekly Weeks 5-8: 4mg weekly Weeks 9-12: 8mg weekly Week 13+: 12mg weekly (maintenance dose) This gradual increase helps minimize side effects while allowing the body to adjust to the compound
Circulation 80 , 551563 (1989)
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