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Upon cessation of treatment and clearance from the body for many xenobiotics that produce hepatocellular hypertrophy, the excess smooth endoplasmic reticulum is removed, presumably by autophagic sequestration (Feldman et al
Haupt KA, Enright AL, Ferdous AS, Kershner AM, Shin H, Wickens M, et al
GI issues: Nausea and constipation are common on Wegovy
Effects on the Heart In 2009, a study with liraglutide showed improved cardiac output and protection against ischemic injury in a mouse model with 28 days follow-up (222)
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