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BMC Glob Public Health 2:63
Gill et al
The increase of intracellular ATP levels hesitates in the closure of plasma membrane K+ channels, thus triggering -cell depolarization
This study found: People who took Contrave lost about 5 or 6% (depending on dose) of body weight compared to a 1.3% loss in those who took a placebo 39 to 48% of people who took Contrave (depending on dose) lost 5% or more of body weight compared to 16% of those who took a placebo In the Contrave Obesity Research II (COR-II) study, participants took either Contrave or a placebo for 56 weeks
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