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LEADER, liraglutide effect and action in diabetes: evaluation of cardiovascular outcome resultsa long-term evaluation
In Quebec, where one in four adults is obese, the current cost of these new drugs (approximately $500 per month) would involve an annual expenditure of several hundred million dollars (in the United States the situation is even worse: the cost of a 72-week course of tirzepatide (15 mg/week) is approximately US$17,000, while the 68-week treatment with semaglutide (2.4 mg/week) is nearly US$23,000!)
In this respect, selenosugars seem to be more feasible candidates, since they might exploit glucose- or other transporters ( + is unlikely to be either effectively transported to the brain due to its positive charge and missing capability of effective metabolization in the brain tissue (Suzuki et al., 2006
Semaglutide injections are available to people with a body mass index (BMI) of 30 or higher, or a BMI of 27 or higher paired with a weight-related health condition such as high blood pressure, type 2 diabetes, obstructive sleep apnea, or high cholesterol levels
US$ 20.24
US$ 25.42
US$ 27.64
US$ 28.22
