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GLP-1 receptor agonists mimic the GLP-1 hormone that is naturally released in the gastrointestinal tract in response to eating, Harvard wrote

It was approved in 1959, making it the oldest FDA-approved weight-loss medication still on the market, and has traditionally been the most commonly prescribed anti-obesity drug in the United States, according to the Obesity Medicine Association

Cannabis used to eat, sleep, reduce nausea, manage pain, or reduce anxiety tells your provider what symptom you are already treating

And people were using things like ChatGPT, but now ChatGPT and all the large language models have shut that down