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Dietary and oral supplementation are the most common ways of achieving adequate B12 levels, but this can be challenging for certain individuals depending on their diet, intestinal health, ability to convert to active forms and other health conditions

Musculoskeletal improvements in strength, range of motion, and pain reduction typically follow over weeks 3 through 6

[7] The effects of high-dose NAD+ on a developing fetus or nursing infant have not been studied, so the therapy is avoided entirely in these situations out of caution